Day 1: 10 mg PO before breakfast, 5 mg after lunch and after dinner, and 10 mg at bedtime Day 2: 5 mg PO before breakfast, after lunch, and after dinner and 10 mg at bedtime Day 3: 5 mg PO before breakfast, after lunch, after dinner, and at bedtime Day 4: 5 mg PO before breakfast, after lunch, and at bedtime Day 5: 5 mg PO before breakfast and at bedtime Day 6: 5 mg PO before breakfast Immediate-release: ≤10 mg/day PO added to disease-modifying antirheumatic drugs (DMARDs) Delayed-release: 5 mg/day PO initially; maintenance: lowest dosage that maintains clinical response; may be taken at bedtime to decrease morning stiffness with rheumatoid arthritis Take with meal or snack High-dose glucocorticoids may cause insomnia; immediate-release formulation is typically administered in morning to coincide with circadian rhythm Delayed-release formulation takes about 4 hours to release active substances; thus, with this formulation, timing of dose should take into account delayed-release pharmacokinetics and disease or condition being treated (eg, may be taken at bedtime to decrease morning stiffness with rheumatoid arthritis) Allergic: Anaphylaxis, angioedema Cardiovascular: Bradycardia, cardiac arrest, cardiac arrhythmias, cardiac enlargement, circulatory collapse, congestive heart failure, fat embolism, hypertension, hypertrophic cardiomyopathy in premature infants, myocardial rupture after recent myocardial infarction, pulmonary edema, syncope, tachycardia, thromboembolism, thrombophlebitis, vasculitis Dermatologic: Acne, allergic dermatitis, cutaneous and subcutaneous atrophy, dry scalp, edema, facial erythema, hyper- or hypopigmentation, impaired wound healing, increased sweating, petechiae and ecchymoses, rash, sterile abscess, striae, suppressed reactions to skin tests, thin fragile skin, thinning scalp hair, urticaria Endocrine: Abnormal fat deposits, decreased carbohydrate tolerance, development of cushingoid state, hirsutism, manifestations of latent diabetes mellitus and increased requirements for insulin or oral hypoglycemic agents in diabetics, menstrual irregularities, moon facies, secondary adrenocortical and pituitary unresponsiveness (particularly in times of stress, as in trauma, surgery, or illness), suppression of growth in children Fluid and electrolyte disturbances: Fluid retention, potassium loss, hypertension, hypokalemic alkalosis, sodium retention Gastrointestinal: Abdominal distention, elevation of serum liver enzymes levels (usually reversible upon discontinuance), hepatomegaly, hiccups, malaise, nausea, pancreatitis, peptic ulcer with possible perforation and hemorrhage, ulcerative esophagitis General: Increased appetite and weight gain Metabolic: Negative nitrogen balance due to protein catabolism Musculoskeletal: Osteonecrosis of femoral and humeral heads, Charcot-like arthropathy, loss of muscle mass, muscle weakness, osteoporosis, pathologic fracture of long bones, steroid myopathy, tendon rupture, vertebral compression fractures Neurologic: Arachnoiditis, convulsions, depression, emotional instability, euphoria, headache, increased intracranial pressure with papilledema (pseudotumor cerebri; usually following discontinuance of treatment), insomnia, meningitis, mood swings, neuritis, neuropathy, paraparesis/paraplegia, paresthesia, personality changes, sensory disturbances, vertigo Ophthalmic: Exophthalmos, glaucoma, increased intraocular pressure, posterior subcapsular cataracts, central serous chorioretinopathy Reproductive: Alteration in motility and number of spermatozoa Untreated serious infections Documented hypersensitivity Varicella Administration of live or attenuated live vaccine (Advisory Committee on Immunization Practices (ACIP) and American Academy of Family Physicians (AAFP) state that administration of live virus vaccines usually is not contraindicated in patients receiving corticosteroid therapy as short-term ( Monitor for hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing syndrome, and hyperglycemia Prolonged use associated with increased risk of infection; monitor Use with caution in cirrhosis, ocular herpes simplex, hypertension, diverticulitis, hypothyroidism, myasthenia gravis, peptic ulcer disease, osteoporosis, ulcerative colitis, psychotic tendencies, renal insufficiency, pregnancy, diabetes mellitus, congestive heart failure, thromboembolic disorders, GI disorders Long-term treatment associated with increased risk of osteoporosis, myopathy, delayed wound healing Patients receiving corticosteroids should avoid chickenpox or measles-infected persons if unvaccinated Latent tuberculosis may be reactivated (patients with positive tuberculin test should be monitored) Some suggestion (not fully substantiated) of slightly increased cleft palate risk if corticosteroids are used in pregnancy Methylprednisolone is preferred in hepatic impairment because prednisone must be converted to prednisolone in liver Prolonged corticosteroid use may result in elevated intraocular pressure, glaucoma, or cataracts May cause impairment of mineralocorticoid secretion; administer mineralocorticoid concomitantly May cause psychiatric disturbances; monitor for behavioral and mood changes; may exacerbate pre-existing psychiatric conditions Monitor for Kaposi sarcoma Pregnancy category: C (immediate release); D (delayed release) Drug may cause fetal harm and decreased birth weight; maternal corticosteroid use during first trimester increases incidence of cleft lip with or without cleft palate Lactation: Of maternal serum metabolites, 5-25% are found in breast milk; not recommended, or, if benefit outweighs risk, use lowest dose Glucocorticosteroid; elicits mild mineralocorticoid activity and moderate anti-inflammatory effects; controls or prevents inflammation by controlling rate of protein synthesis, suppressing migration of polymorphonuclear leukocytes (PMNs) and fibroblasts, reversing capillary permeability, and stabilizing lysosomes at cellular level; in physiologic doses, corticosteroids are administered to replace deficient endogenous hormones; in larger (pharmacologic) doses, they decrease inflammation The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. doxycycline dosage for lyme My prescription says to take the 20 mg Prednisone tab 3 times a day for 5 days. I've heard all kinds of horror stories about steriod therapy I am kinda scared about taking this drug. Is it safe to take this for 5 days straight and then just stopped taking it?? The reason I'm taking it in the first place was because of a trip to the ER where I was diagnosed with acute bronchontis - I also rec'd the antibiotic Zythromax for infection. I've finished the antibiotic but still have four prednisone tablets left to take - should i been weened off of these or just stop?? Please help - I'm really not liking these steriods You must ween off really slowly DO NOT JUST STOP! as you may make your adrenal glands to not work properly, it stops supplying cortisone. Where can i buy acyclovir cream online I was on prednisone ; 60 mg for 5 days,40mg for 5 days,20 mg for 5 days,10mg for 5 days,5mg for 5 days. Now I am finished. What should I expect as after effects. The reason I was given the drug was an extremely bad rash given when I was on amiodarone. buy zithromax pills I took prednisone for 5 days, 40 mg a day. I have been having side effects for the last week. Asked by Ruth 123 Updated 23 December 2017 Topics anxiety, generalized anxiety disorder, prednisone, side effect, fatigue, tremor, blood pressure, heart, heart rate, blood, pressure In general, most people take the drug for a short period of time in order to avoid long-term prednisone side effects. These side effects can usually be avoided by taking lower dosages less than prednisone 20 mg per day or by taking prednisone for less than two weeks. Prednisone is a medication that is often used to treat inflammatory bowel disease (IBD) (Crohn’s disease and ulcerative colitis), as well as a host of other diseases and conditions. It can be very effective in getting acute IBD symptoms under control, but the list of potential side effects that this drug can cause is extensive. The good news is that most prednisone side effects will go away as the dose is lowered and then the drug is stopped altogether. One of the goals of treating IBD is to use prednisone sparingly and to get patients off it as soon as possible. Knowing about the potential for side effects goes a long way towards minimizing them and coping with them when they do happen. If your doctor has prescribed prednisone, it's because the benefits of the drug outweigh the risks of the side effects. Below is a discussion of the potential prednisone side effects, when they occur, which are temporary, and which could be permanent. Prednisone is a synthetic steroid with potent anti-inflammatory effects that is used to treat inflammatory types of arthritis and other conditions. Like other corticosteroids, prednisone works by lowering the activity of the immune system. The drug must be taken according to directions, since misuse, long-term use, or high doses can lead to undesirable side effects. Similarly, discontinuation of the drug in the proper way can help prevent symptoms of prednisone withdrawal. Cortisol is a steroid hormone that regulates a wide range of processes throughout the body, including metabolism and the immune response. It also plays a very important role in helping the body respond to stress. If you take prednisone for more than a few weeks, your adrenal glands will decrease the natural production of cortisol. Prednisone 20 mg 5 days Prednisone 20 mg.5 days.are the side effects., I took prednisone for 5 days, 40 mg a day. I have been having. 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