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    Topical Minoxidil is a product which is used to treat and/or prevent hair loss. Minoxidil is the ONLY FDA -approved TOPICAL treatment for male pattern hair loss. High strength PRESCRIPTION Minoxidil IS MEDICALLY PROVEN to STOP hair loss and REGROW hair (1). Minoxidil effectiveness is dose dependent and the higher the dose the better the hair regrowth. Minoxidil topical is prescribed to stimulate hair growth in men and women with a specific type of baldness known as androgenetic alopecia (popularly known as male pattern baldness or female pattern baldness). It is not known how minoxidil works, however by stimulating hair follicle cells and by dilating the blood vessels in the scalp, it appears that Minoxidil mimics the actions of Nitric Oxide. It increases the flow of blood, nutrients, and other important substances to hair follicles. Department of Pharmacology and Therapeutics, Kufa College of Medicine, Kufa, Iraq Received 2 December 2013; Accepted 23 January 2014; Published 9 March 2014Academic Editors: R. It was discovered to have the side effect of hair growth and reversing baldness. To compare the stimulatory effect of Ketoconazole, Minoxidil, and Minoxidil with Tretinoin on hair growth in a mouse model. Coat hairs on the dorsal skin of seven weeks old male mice were gently clipped and then stained by using commercial dye. Minoxidil is a vasodilatory medication used primarily as antihypertensive drug. Recently topical use of 2% Ketoconazole solution has been reported to have a therapeutic effect on androgenic alopecia. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Tretinoin is commonly used topically for acne treatment and in the treatment of photoaging. These mice were divided into four groups each of five treated with topical application of ethanol 95%, Ketoconazole solution 2%, Minoxidil solution 5%, and Minoxidil with Tretinoin solution 0.1%, respectively. The drugs were applied once daily for three weeks, the clipped area was photographed, and the ratio of regrown coat area was calculated. The results demonstrated that Ketoconazole, Minoxidil, and Minoxidil with Tretinoin had a significant stimulatory effect on hair growth compared with the control group and Minoxidil was the most effective drug among them. Androgenic alopecia is a partial or complete loss of hair that occurs in a progressive pattern in genetically predisposed individuals [1].

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    Promotive Effect of Topical Ketoconazole, Minoxidil, and Minoxidil with., Retinoic Acid & Minoxidil Hair Loss Cure, All You Need to Know.

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    • PDF The Additive Effects of Minoxidil and Retinol on Human Hair.
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