It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil blog Hydroxychloroquine sulfate 200 Can plaquenil treat ms What is the use of chloroquine phosphate The coadministration of the two drugs did not affect chloroquine or desethylchloroquine pharmacokinetics but increased plasma primaquine concentrations significantly P ≤ 0.005; the geometric mean 90% confidence interval CI increases were 63% 47 to 81% in maximum concentration and 24% 13 to 35% in total exposure. The interaction evaluation shows that chloroquine has significant effects on primaquine pharmacokinetics, whereas primaquine has negligible effects on the disposition of chloroquine. Coadministration of chloroquine increased peak primaquine concentrations by approximately 63% and overall primaquine exposure by 24%. Chloroquine taken in the dose recommended for malaria prophylaxis can reduce the antibody response to primary immunization with intradermal human diploid-cell rabies vaccine. Praziquantel In a single-dose interaction study, Chloroquine has been reported to reduce the bioavailability of praziquantel. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Chloroquine interactions Chloroquine Indications, Side Effects, Warnings -, Pharmacokinetic Interactions between Primaquine and Chloroquine Plaquenil cause weight gainCan plaquenil cause psoriasis The following interactions have been observed on treatment with the structurally related substance chloroquine phosphate, and therefore cannot be ruled out for hydroxychloroquine. Praziquantel. Chloroquine has been reported to reduce the bioavailability of praziquantel. Antacids And Kaolin Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Chloroquine - Prescription Drug Information, Interactions & Side Effects. Plaquenil Oral Interactions with Other Medication. Chloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria and to prevent malaria in areas or regions where chloroquine is known not to work resistance. We would like to show you a description here but the site won’t allow us. Chloroquine enters the red blood cell by simple diffusion, inhibiting the parasite cell and digestive vacuole. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion.