Chloroquine interactions

Discussion in 'Without A Doctor Prescription' started by S0meT1me, 06-Mar-2020.

  1. GeorgeR New Member

    Chloroquine interactions


    It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world.

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    The coadministration of the two drugs did not affect chloroquine or desethylchloroquine pharmacokinetics but increased plasma primaquine concentrations significantly P ≤ 0.005; the geometric mean 90% confidence interval CI increases were 63% 47 to 81% in maximum concentration and 24% 13 to 35% in total exposure. The interaction evaluation shows that chloroquine has significant effects on primaquine pharmacokinetics, whereas primaquine has negligible effects on the disposition of chloroquine. Coadministration of chloroquine increased peak primaquine concentrations by approximately 63% and overall primaquine exposure by 24%. Chloroquine taken in the dose recommended for malaria prophylaxis can reduce the antibody response to primary immunization with intradermal human diploid-cell rabies vaccine. Praziquantel In a single-dose interaction study, Chloroquine has been reported to reduce the bioavailability of praziquantel.

    For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too.

    Chloroquine interactions

    Chloroquine Indications, Side Effects, Warnings -, Pharmacokinetic Interactions between Primaquine and Chloroquine

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  4. The following interactions have been observed on treatment with the structurally related substance chloroquine phosphate, and therefore cannot be ruled out for hydroxychloroquine. Praziquantel. Chloroquine has been reported to reduce the bioavailability of praziquantel. Antacids And Kaolin

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    Chloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria and to prevent malaria in areas or regions where chloroquine is known not to work resistance. We would like to show you a description here but the site won’t allow us. Chloroquine enters the red blood cell by simple diffusion, inhibiting the parasite cell and digestive vacuole. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion.

     
  5. Zerling New Member

    Selected from data included with permission and copyrighted by First Databank, Inc. Hair Loss - General - Sjogren's Syndrome Support Plaquenil Hydroxychloroquine Side effects, Images, Uses. Hair loss in Plaquenil how severe and when it was recovered.
     
  6. altrum Moderator

    Plaquenil Side Effects - GoodRx Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

    Rx Side Effects New Plaquenil Guidelines and More.