Drugs administered with chloroquine

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  1. Anatoly_Sokolov Well-Known Member

    Drugs administered with chloroquine


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    As a result, the released drug is still absorbed systemically. Chloroquine CQ is commonly used to prevent and treat malaria caused by Plasmodium P vivax, P. ovale, and P. malariae. The drug should be administered with caution to patients having G-6-PD glucose-6 phosphate dehydrogenase deficiency. Auditory Effects. In patients with preexisting auditory damage, chloroquine should be administered with caution. In case of any defects in hearing, chloroquine should be immediately discontinued, and the Chloroquine is a highly effective schizontocide, while primaquine has weaker asexual-stage activity 3 but is the only generally available drug with hypnozoitocidal properties, i.e. it kills dormant liver stage parasites and prevents relapse radical cure 1.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Drugs administered with chloroquine

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  5. Popular drugs based on chloroquine phosphate also called nivaquine are Chloroquine FNA, Resochin and Dawaquin. Chloroquine is a 4-aminoquinolone compound with a complicated and still unclear mechanism of action.

    • Antimalarial medication - Wikipedia.
    • Pharmacokinetic Interactions between Primaquine and..
    • CHLOROQUINE PHOSPHATE, USP - Food and Drug Administration.

    Drug interactions Antacids - may reduce absorption of chloroquine. Kaolin - may reduce absorption of chloroquine. Cimetidine - may inhibit metabolism of chloroquine; increasing levels of chloroquine in the body. Ampicillin - levels may be reduced by chloroquine. Cyclosporine - levels may be. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis. Chloroquine Aralen Quinacrine Atabrine What are anti-malarial drugs, and why are they used to treat lupus? Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria.

     
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    This article focuses upon hydroxychloroquine retinopathy. Chloroquine was originally used as an anti-malarial therapeutic. The Risk of Retinal Toxicity with Plaquenil Plaquenil Hydroxychloroquine - Side Effects, Dosage. What can Hydroxychloroquine Plaquenil do to my eyes?
     
  7. Plaquenil is the brand name for the prescription drug hydroxychloroquine. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Plaquenil Uses, Dosage & Side Effects - Plaquenil Hydroxychloroquine - Side Effects, Dosage.
     
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    Buy Aralen Chloroquine safely online with special offers Buy Aralen with home delivery online. How to buy Chloroquine safely. Buy cheap Aralen Chloroquine online without prescription, find out more information about lowest prices and offers, free shipping, best quality generic medications

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  9. ekwatt Well-Known Member

    DRUG RESISTANT MALARIA CURRENT STATUS DRUG RESISTANT MALARIA Chloroquine resistance Chloroquine is ineffective in almost all malaria endemic countries In India chloroquine resistance was first detected in 1973 in Assam. Severe in northeast and southeastern regions of India with high morbidity and mortality.

    History of antimalarials Medicines for Malaria Venture