While the mechanism is poorly understood, pregnant women have a reduced immune response and therefore less effectively clear malaria infections. In addition, malaria parasites sequester and replicate in the placenta. Does plaquenil reduce rheumatoid factor in patiences with sjogrens Stopping hydroxychloroquine sulfate tabs It appears to be safe for use during pregnancy. Chloroquine is a member of the drug class 4-aminoquinoline. It works against the asexual form of malaria inside the red blood cell. Chloroquine was discovered in 1934 by Hans Andersag. Find patient medical information for Chloroquine Injection on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Chloroquine is an antimalarial medication which is used in the treatment as well as prophylaxis of malaria. This medicine is not recommended in patients with the eye disease. Liver function and blood cell count monitoring is necessary while receiving this medicine. Know Chloroquine uses, side effects, dosage, contraindications, benefit, interactions, purpose, drug interactions, precautions. Malaria infection during pregnancy can lead to miscarriage, premature delivery, low birth weight, congenital infection, and/or perinatal death. Pregnant women are three times more likely to develop severe disease than non-pregnant women acquiring infections from the same area. Chloroquine dose during pregnancy CHLOROQUINE PHOSPHATE, USP, Chloroquine Injection Uses, Side Effects, Interactions. Plaquenil and neuropathyHydroxychloroquine and yellow sweat stainsChloroquine and proguanil dose Use in pregnancy. There is no evidence that chloroquine is harmful in prophylactic doses during pregnancy. Because of the susceptibility of pregnant women to falciparum malaria, it should be used at the recommended dosage for both prophylaxis and treatment wherever chloroquine-sensitive malaria is prevalent. Adverse effects WHO Model Prescribing Information Drugs Used in Parasitic.. Chloroquine - Uses, Dosage, Side Effects, Composition & more.. Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs. Hydroxychloroquine Pregnancy Warnings Animal studies have revealed evidence of fetal harm. Use of chloroquine and other 4-aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus. In areas where P. falciparum is resistant to chloroquine, mefloquine is also suitable during pregnancy. Note that in some areas of south-east Asia, there are areas where P. falciparum is resistant to mefloquine, which may prevent its suitability as a prophylactic in this region. There are no adequate and well-controlled studies evaluating the safety and efficacy of chloroquine in pregnant women. Usage of chloroquine during pregnancy should be avoided except in the suppression or treatment of malaria when in the judgment of the physician the benefit outweighs the potential risk to the fetus. REFERENCES. 1.