It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria. Can plaquenil help with fatigue Is hydroxychloroquine an immune modulator The Lupus Foundation of America works to improve the quality of life for all people affected by lupus through programs of research, education, support and advocacy. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. It is also used to treat acute and chronic rheumatoid arthritis. Hydroxychloroquine is used to treat discoid lupus erythematosus (DLE) or systemic lupus erythematosus (SLE or lupus). What is plaquenil diagnosed for Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Hydroxychloroquine Plaquenil Do i need hydroxychloroquine with methotrexatePlaquenil dosage for sjogren& 39How many hours does plaquenil work in the bodyIcd for starting plaquenil medicationChloroquine injection brand name The diagnosis of Sjögren’s syndrome requires demonstration of an autoimmune disease that is adversely affecting the function of the glands that produce tears and saliva. Dry eyes and dry mouth are the most common symptoms. Diagnosis of Sjögren's Syndrome - Johns Hopkins Sjogrens Center. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. How is plaquenil hydroxychloroquine used to treat lupus?. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. You will likely have to take additional medications to keep your rheumatoid arthritis in control. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. When the first biologic DMARD received FDA-approval in 1998, and as other biologics followed in subsequent years, it appeared as though Plaquenil would become less prescribed.