I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Hydroxychloroquine in canada Plaquenil and nail changes How much plaquenil should i take We study how severe was Withdrawal syndrome, when it was recovered, drug effectiveness, race, and more among people who take Plaquenil. This study is created by eHealthMe based on reports of 1,993 people who have side effects when taking Plaquenil from sources other than FDA, and is updated regularly. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Plaquenil side effects when stopping The Risk of Retinal Toxicity with Plaquenil, Plaquenil Side Effects - GoodRx Plaquenil taperChloroquine dengueChloroquine resistant vivax malaria treatmentPlaquenil hydrochloroquine These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Let me tell you what weaning down from Plaquenil is like.. Lawchick my name is chellety and yes i have had horrbile side effects with the plaquenil they say it is suppose to be the best medication you can use for lupus but i was getting symptoms of that of a diabetes patient like gout in my toe, it was horrible pain and burning OMG, sounds weird but i stop taking the plaquenil and stuck to predisone. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Withdrawal syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Lyrica, and have Fibromyalgia. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly.