Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. What are altered effects of hydroxychloroquine Plaquenil crohn's disease Plaquenil and sarafem interactions Men, especially men with increased muscle mass who weigh less than 176 pounds would be on 300 mg a day per these recommendations. Since Plaquenil distributes in lean tissues and not fat, theoretically I would think they'd be at lower risk of toxicity, and I wonder if it may be better to use ideal body weight IBW instead for them. The American Academy of Ophthalmology AAO advises weight-based dosing of 6.5 mg/kg, with an upper limit of 400 mg/day. Exceptions are individuals of short stature and obese patients, for whom the AAO advises calculating dosage based on ideal body weight for height15. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil weight based dosing Best of 2018 Hydroxychloroquine Being Over-Dosed with New Guidelines., The Role of Hydroxychloroquine Blood Levels in SLE RheumNow. Hydroxychloroquine allergic reactionChloroquine phosphate uspGeneric plaquenil price By the old standards, obese people, if dosed by their actual weight, could be overmedicated, Dr. Marmor said. If you’re short, the standard prescription of 200 mg of Plaquenil, twice daily, is too much, he said. The recommended dosage is no more than 6.5 mg/kg/day, using the standard known as “ideal weight,” which factors in height. Dr. Rx Side Effects New Plaquenil Guidelines and More - American Academy.. Taking Plaquenil for Rheumatoid Arthritis. Hydroxychloroquine Plaquenil. The rheumatologist prescribed a toxic dose of HC based on the patient’s height and weight. The patient was 5 ft. tall, with an ideal body weight of 123 pounds 55.9 kg, see Table 2 and a maximal daily safe dose of 55.9 x 6.5=363 mg/d of HC. The usual hydroxychloroquine dose that is prescribed is 400 mg/day. For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. As one can see, the height that corresponds to an ideal body weight of 135 pounds varies across the formulas. Acute attack Dosage is based on body weight. The typical starting dose is 13 mg/kg maximum dose 800 mg. Additional doses of 6.5 mg/kg maximum dose 400 mg should be given at the following times 6 hours after the first dose, 24 hours after the first dose, and 48 hours after the first dose.