Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. How much is to much plaquenil Can plaquenil cause thrush Can hydroxychloroquine cause weight gain hair loss The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine Plaquenil. This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day 200 bid. Mg/kg base not to exceed 400 mg 310 mg base PO weekly, starting 2 weeks before exposure and continued for 4 weeks after departure from area With prolonged therapy, obtain CBCs periodically. Treatment of Uncomplicated Malaria Adults 800 mg 620 mg base followed by 400 mg 310 mg base at 6 hours, 24 hours and 48 hours after the initial dose total 2000 mg hydroxychloroquine sulfate or 1550 mg base. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Dosage of plaquenil Hydroxychloroquine - Wikipedia, Plaquenil hydroxychloroquine sulfate dosing, indications. Does plaquenil suppress immune system further in an immunosuppressed personEyes hydroxychloroquineCan plaquenil cause ptosis Avoid coadministration of hydroxychloroquine and doxorubicin if possible. If not possible, closely monitor for increased side effects of doxorubicin including myelosuppression and cardiotoxicity. Dronedarone Severe Dronedarone administration is associated with a dose-related increase in the QTc interval. The increase in QTc is approximately 10 milliseconds at doses of 400 mg twice daily the FDA-approved dose and up to 25 milliseconds at doses of 1600 mg twice daily. Plaquenil hydroxychloroquine sulfate dose, indications.. Plaquenil Dosage Guide -. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine generally is given to adults in doses of 200 mg or 400 mg per day. In some cases, higher doses can be used. Your doctor may gradually increase or decrease your dosage over time to find the right levels for your specific symptoms and needs while having the least amount of negative side effects. Melton & Thomas describe the typical safe Plaquenil dosage this way The usual dosage is two 200mg tablets per day. This is generally a "safe" dose for patients having a lean body weight of at least 135 lbs. The generally-regarded safe dosage is 6.5mg/kg/qd, thus the 135 lb. safety threshold. Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar.