Chloroquine pharmacokinetics

Discussion in 'International Pharmacy' started by abrand, 01-Mar-2020.

  1. Aldram XenForo Moderator

    Chloroquine pharmacokinetics


    Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take chloroquine with all of your drugs and health problems.

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    Pharmacokinets of Chloroquine. Absorption It is well absorbed after oral administration. Distribution It is distributed in protein bound form and concentrated in melanin containing cells. Metabolism some drugs undergo metabolism in the liver. Excretion It is excreted mainly through urine. Pharmacology and Biochemistry 8.3 ATC Code. Excretion of chloroquine is quite slow, but is increased by acidification of the urine. 8.6 Biological Half-Life. The plasma half-life of chloroquine in healthy individuals is generally reported. 8.7 Mechanism of Action. The mechanism behind the. Oct 01, 2018 Chloroquine is deposited in the tissues in considerable amounts. In animals, from 200 to 700 times the plasma concentration may be found in the liver,spleen, kidney, and lung; leukocytes also concentrate the drug. The brain and spinal cord, in contrast, contain only 10 to 30 times the amount present in plasma.

    For all uses of chloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor.

    Chloroquine pharmacokinetics

    Pharmacokinetics, Pharmacodynamics, and Allometric Scaling., Chloroquine C18H26ClN3 - PubChem

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  3. Sep 01, 2019 Hydroxychloroquine, like chloroquine, is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. It can also inhibit certain enzymes by its interaction with DNA.

    • Hydroxychloroquine Tablets - FDA prescribing information..
    • Chloroquine - FDA prescribing information, side effects and uses.
    • Pharmacokinetics/pharmacodynamics of chloroquine and..

    Effects of chloroquine? Chloroquine is a relatively well-tolerated. medicine. The most common adverse reactions reported are stomach pain, nausea, vomiting, and headache. These side effects can often be lessened by taking chloroquine with food. Chloroquine may also cause itching in some people. All medicines may have some side effects. Pharmacology 4,828 Views Chloroquine is one of the oldest anti-malarial agent, effectively used in malarial infections. P. falciparum and vivax are the sensitive types. It is a rapidly acting drug, targeting the asexual stage. Professional guide for Chloroquine. Includes pharmacology, pharmacokinetics, contraindications, interactions, adverse reactions and more.

     
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