Plaquenil oct of macula

Discussion in 'Hydroxychloroquine' started by Kamilla, 28-Feb-2020.

  1. sonnec XenForo Moderator

    Plaquenil oct of macula


    One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus.

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    Macular degeneration is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years, also take medication Humira, and have Joint deposit Recent advances in spectral-domain optical coherence tomography SD-OCT allow for cross-sectional imaging of the retina in vivo to resolutions of 5 to 10 μm. 11 – 16 Adaptive optics AO imaging corrects for ocular aberrations and allows for direct visualization of the photoreceptor mosaic in vivo to resolutions of ≤2 μm. 17 – 20 This report presents the results of SD-OCT and AO imaging on two patients with known hydroxychloroquine retinopathy. SD Spectral Domain OCT With early Hydrochloroquine retinopathy, SD-OCT can detect outer layer retinal abnormalities Specifically, SD-OCT can detect loss of the perifoveal photoreceptor inner segment/outer segments line PIL At the macula, an ovoid appearance can appear described as “flying saucer” sign by Chen, et al18 ILM IPL OPL

    It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress.

    Plaquenil oct of macula

    Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Spectral-Domain Optical Coherence Tomography and Adaptive.

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  6. Ocular signs – Anterior segment - vortex keratopathy Fundus – bilateral multiple, yellow, crystalline, ring like deposits in the maculae. These persists even on cessation of treatment, macular edema, punctate retinal pigmentary changes Work up FFA – late focal staining in the macula consistent with CME.

    • Drug induced maculopathy - EyeWiki.
    • Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy.
    • Plaquenil Side Effects on Your Eyes and Vision.

    Spectral-domain optical coherence tomography is required to detect early plaquenil-induced structural damage to the macular region. The following instruments can display imaging data in different reports and formats. SPECTRALIS OCT by Heidelburg Engineering; CIRRUS OCT by Carl Zeiss Meditec; RTVue OCT by Optovue Hydroxychloroquine Macular Toxicity Hydroxychloroquine is an immunomodulating drug that is commonly used in treating collagen vascular diseases such as rheumatoid arthritis and systemic lupus erythematosus. I have only been taking Hydroxychloroquine for just over a year and have had no problems. I told the rheumatologist that I had early stages macular degeneration but they said it was not a problem. Recently i have had eye problems, my last eye test was January, so I went back to the optician who sent me to eye casualty.

     
  7. atoty Well-Known Member

    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite. Chloroquine Phosphate Tablet - Uses, Side-effects, Reviews. Chloroquine Phosphate Side Effects - GoodRx Chloroquine Oral Route Side Effects - Mayo Clinic
     
  8. Llyt Guest

    The resource you are looking for (or one of its dependencies) could have been removed, had its name changed, or is temporarily unavailable. Plaquenil Prices, Coupons & Savings Tips - GoodRx Hydroxychloroquine Oral Uses, Side Effects, Interactions. Hydroxychloroquine - Side Effects, Dosage, Interactions.
     
  9. partizan2008 XenForo Moderator

    Hydroxychloroquine Plaquenil Toxicity and. Chloroquine and hydroxychloroquine both belong to the quinolone family and share similar clinical indications and side effects, including retinal toxicity. Chloroquine-induced retinal toxicity was first described in 1959 and the retinal toxic effects of hydroxychloroquine were later described in 1967 3, 4.

    Rx Side Effects New Plaquenil Guidelines and More.
     
  10. MegaMoney Moderator

    Hydroxychloroquine-Induced Pigmentation in Patients With. Hydroxychloroquine-induced pigmentation lesions usually begin after a few months or years of treatment. When we compared our patients with the controls, we found no significant association with the duration of HCQ treatment or with the cumulative dose of HCQ.

    A Randomized Study of the Effect of Withdrawing.