These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hydroxychloroquine and l lysine Plaquenil 200 mg uses Plaquenil for osteoarthritis Jun 09, 2006 Patients with rheumatoid arthritis RA, an inflammatory arthritis that can destroy joint structures, are often on multiple medications to control disease activity. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Plaquenil bleeding Plaquenil and Nose Bleeds. ProHealth Fibromyalgia, ME/CFS., Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Hydroxychloroquine side effects dry eyesChloroquine dose per kg If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell. Common and Rare Side Effects for Plaquenil Oral. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Re Plaquenil side effects Plaquenil made me a bit nauseated in the beginning but that wnet away within a few weeks. You usually need to be on Plaquenil for a few mon ths for it to take effect. Jul 27, 2017 Breakthrough bleeding is when menstrual bleeding occurs between periods. It can be light spotting or just as heavy as your typical period. This can happen when taking an oral contraceptive. This can become a very frustrating problem for women on the pill, because one of the reasons they may be taking it in the first place is to regulate their cycles. Get emergency medical help if you have signs of an allergic reaction hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina.