Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. What is the use of chloroquine phosphate What is plaquenil diagnosed for What is chloroquine injection Plaquenil generic date Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia. Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 Have you had your thyroid tested recently? Swinging hypothyroid can cause mood swings, depression and constipation. I took Plaquenil for six years and am really not sure whether I suffered any side effects or not. I think it may have contributed to tinnitus and I came off i9t in case it was contributing to balance issues. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and mood Hydroxychloroquine Plaquenil — Canadian Hair Loss Foundation, Hydroxychloroquine Plaquenil - Ok to stop taking hydroxychloroquine Balances out the steroids and im guessing, the Plaquenil, because I had weird issues before with Plaquenil and this time I don't. I know they can be addictive so im careful, and I respect them, I try to skip if I can, but between anxiety from pills helping me to live better, and addicted to nerve pills, I choose all the above and lead a calm life Anxiety and Plaquenil Has anyone experienced mood. - LUPUS UK. Plaquenil causing mood changes and depression?. Does Plaquenil affect your temperament? - LUPUS UK. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Similarly, one study reported that 16 women who’d taken hydroxychloroquine or chloroquine, or a combination of the agents, showed no improvement seven years after stopping drug therapy, and progression occurred in six of the cases. 2 Hydroxychloroquine received an overall rating of 7 out of 10 stars from 368 reviews. See what others have said about Hydroxychloroquine, including the effectiveness, ease of use and side effects. Plaquenil and Mood swings - a study from real-world data. Summary Mood swings is found among people who take Plaquenil, especially for people who are female, 40-49 old, have been taking the drug for 1 - 2 years, also take medication Enbrel, and have Pain.