Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Purpose of plaquenil in lupus Chloroquine and neuropathy The benefits of Plaq take from 2 - 6 months. However the side effects / stomach issues join the party right at the start. From day 1 or 2 this med made me, well, kinda queasy. I was not nauseous, but I was not interested in eating. Then the real fun began -- massive gas, and oh yeah the diarrhea. Imodium AD was the way I got through the day. What are the side effects of hydroxychloroquine Plaquenil? Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Common Plaquenil side effects - a study from FDA data Summary In this review, we analyze Plaquenil side effects by the time on the drug, gender and age of the people who have side effects while taking Plaquenil. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Lupus and plaquenil side effects Plaquenil Uses, Dosage & Side Effects -, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Stopped taking plaquenil Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. Although they are uncommon, Plaquenil has side effects that may affect your eyes. Plaquenil Side Effects on Your Eyes and Vision. Common Plaquenil side effects a study from FDA data - eHealthMe. Hydroxychloroquine Plaquenil Success, Reviews and Side Effects. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Common Side Effects of Plaquenil. Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache; Loss of appetite; Dizziness; Nausea The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Rarely, hydroxychloroquine can lead to anemia in some individuals.