It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Chloroquine brain tumor Plaquenil revised dosing Plaquenil injections Plaquenil 200 mg reviews The answer was that while Hydroxychloroquine, the generic name for Plaquenil and the tablet I take in the same dose as yourself i.e. 200mg a day at the moment, is a disease modifying drug and an anti-malarial, it is also a mild immunosuppressant too. So this could be why your immune system is so low at the moment. Plaquenil is NOT known to start working that fast. It takes anywhere from 4-6 months before the affects of Plaquenil are seen/felt. This is the case with everyone I know that takes it. My rheumy has saidand everything I've read on Plaquenil that Plaquenil NEEDS that amount of time to build in your system before it stats to have beneficial effects. Mar 23, 2014 Plaquenil is not thought to have a strong effect on the immune system with regard to illnesses etc.far as I am aware. I am sure others will be on to share any similar experiences however, I found the plaquenil, if anything very weak for my MCTD.needed steroids too whilst it was kicking in.then Cellcept etc etc Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Does plaquenil lower your immune system Reasonably Well Plaquenil FAQ, Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly? Chloroquine for raHydrocodone and plaquenilChloroquine and proguanil dose Jun 01, 2018 Plaquenil is an immunomodulatory drug DMARD that works by suppressing the immune system to prevent it from damaging tissues and joints. The immune system helps protect the body from harmful substances such as infectious agents and bacteria. Plaquenil. Plaquenil and immune system Lupus Forums at The Lupus Site. Hydroxychloroquine Plaquenil. Aug 02, 2010 Plaquenil works by suppressing the immune system. Unfortunately you can't tell it to attack just the germs so you suppress all of its function to spare your healthy tissue- in your husband's case, his eyes, mouth, throat. NOTE Plaquinil and hydroxychloroquine are essentially the same drug. The same effects should be expected from both drugs. 2. No, his immune system should not be forever compromised. A recent large study of people with cardiovascular disease found that hydroxychloroquine Plaquenil does not increase the risk of infection and methotrexate increases the risk of infection only slightly. Howdy LadyDi, sorry you are having problems. Plaquenil is what is call an immune modifier. It is not a immune suppressant. Originally it was used to prevent Malaria. Then it was discovered to be effective for the treatment of Lupus. Plaquenil has the least amount of side affects in treating auto immune disorders.