Chloroquine phosphate toxic

Discussion in 'Chloroquine' started by Pixels, 01-Mar-2020.

  1. needlock XenForo Moderator

    Chloroquine phosphate toxic


    Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention.

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    CHLOROQUINE sulfate or phosphate oral Given that resistance of P. falciparum to chloroquine is widespread, this drug must not be used for the treatment of falciparum malaria in Africa, South America, Asia and Oceania. Chloroquine is very rapidly and completely absorbed after ingestion. Toxic doses of chloroquine can be fatal. As little as 1 g may be fatal in children. Toxic symptoms can occur within minutes. Irreversible retinal damage observed in some patients; significant risk factors for retinal damage include daily doses of chloroquine phosphate 2.3 mg/kg of actual body weight, durations of use.

    Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine.

    Chloroquine phosphate toxic

    Chloroquine and Hydroxychloroquine Toxicity Practice., CHLOROQUINE PHOSPHATE TABLETS, USP 250 MG and 500 MG

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  5. Overdose. Chloroquine is very toxic in overdosage; overdosage is extremely hazardous and difficult to treat. Urgent advice from the National Poisons Information Service is essential. Life-threatening features include arrhythmias which can have a very rapid onset and convulsions which can be intractable.

    • CHLOROQUINE Drug BNF content published by NICE.
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    Significant risk factors for retinal damage include daily doses of chloroquine phosphate greater than 2.3 mg/kg of actual body weight, durations of use greater than five years, subnormal glomerular. Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin. Antacids and kaolin can reduce the absorption of chloroquine; separate by 4 hours. Concomitant use of cimetidine should be avoided. Chloroquine phosphate is calculated as the base. Each 250 mg tablet of chloroquine phosphate is equivalent to 150 mg base and each 500 mg tablet of chloroquine phosphate is equivalent to 300 mg base.

     
  6. slemmy XenForo Moderator

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  7. Nigerians reacts hilariously as it's revealed that Chloroquine. In a three-page paper published in Cell Research, scientists at the Wuhan Institute of Virology’s State Key Laboratory of Virology wrote that both Chloroquine and the antiviral Remdesivir were, individually, “highly effective” at inhibiting replication of the novel coronavirus in cell culture.

    A chloroquine-induced macrophage-preconditioning strategy for improved.