Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine during pregnancy Hydroxychloroquine surfactant protein c deficiency Can chloroquine go through skin Serious side effects. blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or bruising. blue-black skin color. muscle weakness. hair. Common side effects Nausea and diarrhea This can often can be combatted by taking Plaquenil with food or milk. Dizziness Precautions with this side effect Do not drive, use machinery. Cramps. Headache. Dry skin. Loss of appetite. Plaquenil hydroxychloroquine Remove Plaquenil from your drug comparison. Prednisone Remove Prednisone from your drug comparison. Prescribed for Lyme Disease - Arthritis, Dermatomyositis, Malaria, Malaria Prevention, Rheumatoid Arthritis, Systemic Lupus Erythematosus. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil and prednisone side effects Plaquenil Oral Uses, Side Effects, Interactions., Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Hydroxychloroquine side effects nhsMedicare allowable ocular testing for chloroquine therapyCommon ingredients of chloroquine It is created by eHealthMe based on reports of 13,785 people who have side effects when taking Prednisone and Plaquenil from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. Prednisone and Plaquenil drug interaction Lupus nephritis.. Plaquenil vs Prednisone Comparison -. Protecting your eyesight when taking Plaquenil Lupus.. Hi Ang, you should speak to your doctor about any symptoms and medication side effects. reply. By Connie Rifenburg June 3, 2015 at pm. Ang, I had hair loss pretty severe when I first started on Prednisone, Plaquenil, and Methotrexate. I guess it may depend on the dosage, and hopefully your hair loss will stop as mine did after a few months. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about. Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye;. RARE side effects.