Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxychloroquine with all of your drugs and health problems. How chloroquine causes itch How long for plaquenil to work While skin is damp, apply moisturizing lotion. Apply over-the-counter 1 percent hydrocortisone cream twice daily to calm redness, itching, and swelling. People with RA face an increased risk of infection, so if you have a widespread, blistering sunburn, seek medical help, and do not scratch. Rash from a phototoxic reaction is mainly confined to the sun-exposed area of the skin. A phototoxic reaction typically clears up once the drug is discontinued and has been cleared from the body, even after re-exposure to light. The plaquenil has helped with my sun sensitivity, fatigue. "I was Dx with lupus about 17 years ago and have been on and off plaquenil the entire time. I also have urticarial vasculitus, sjogerns and recently my rheumy suspects ra. The plaquenil has helped with my sun sensitivity, fatigue and rashes. For all uses of hydroxychloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Plaquenil and sun rash Plaquenil Uses, Dosage & Side Effects -, Sun-Sensitive Drugs Photosensitivity to Drugs - MedicineNet Chloroquine interactions with birth control Plaquenil has beneficial effects on 3 major aspects of lupus; skin rashes, aches & pains and fatigue. It has also been found to help in a number of other features of the disease, though less predictably. It is very effective in the treatment of a whole variety of lupus skin rashes, particularly those found to be worsened by sunlight. Plaqunil rash -. Plaquenil and Sun Sensitivity - Reviews. Common and Rare Side Effects for Plaquenil Oral. This can trigger symptoms such as skin rashes, itching, and burning. Excess sun exposure can also cause flares in systemic lupus, triggering symptoms such as joint pain, weakness, and fatigue. The malaria medication hydroxychloroquine Plaquenil may ease the symptoms of some types of sun allergies. Therapy If you have a severe sun allergy, your doctor might suggest gradually getting your skin used to sunlight each spring. I got this after about 5 weeks, mine was a blistery rash and it was only on my shoulders, upper chest and upper back. My doctor said it was photodermatitis and caused from a sensitivity to the sun caused by the plaquenil.