Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil uses for lupus What happens if you take too much hydroxychloroquine Here are the three most common antimalarial drugs prescribed for lupus Hydroxychloroquine Plaquenil This is the most commonly prescribed antimalarial. Chloroquine Aralen This drug has been known to have more serious side effects. Quinacrine Atabrine Quinacrine is another. The alternative to Plaquenil is a slightly different anti malarial called Quinacrine. Plaquenil replaced Quinacrine formerly called Atabrine for anti malarial prophylaxis so now the Quinacrine has to be made up into pills or gel capsules by a compounding pharmacy. Hello! Here is a short list Prednisone, Imuran, Remicade, Methotrexate Later sidesteps Prednisone's side effects, which include weight gain, mood swings, diabetes and eye problems, such as cataracts. I hope this was helpful enough. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Alternative meds than plaquenil Safe, Natural Alternatives to Arthritis Drugs Top Doc., Discontinued Plaquenil.other options? How does plaquenil work for sjogren'sPlaquenil lupus en espanol I "know" I need some meds, but cannot tolerate Plaquenil. Wondering if anyone has come across something "natural" that mimics it. Thanks & LIGHT*****carole - Hi, Carole. When I started Plaquenil, my GI system was in an uproar. But it usually was anyway. I didn't realize, until I saw Dr. Natural" alternative to Plaquenil. - HealthBoards. Alternatives to plaquenil Anti-Inflammatories.. Taking Plaquenil for Rheumatoid Arthritis. Hydroxychloroquine Plaquenil hydroxychloroquine. 4 alternatives. Arava leflunomide. methotrexate methotrexate. Sulfasalazine sulfasalazine. chloroquine chloroquine. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Effectively prevents and treats malaria, and treats a certain type of intestinal infection but can cause serious side effects in certain people. Responses 3 The links below have names of medicines which may be used to treat RA or Lupus. yes they also use a combonation of prednisone and cyclosporine for both of those plus several other mctd.