It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Hydroxychloroquine and chloroquine Plaquenil and vision problems Aug 14, 2017 Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. I have a question to ask anyone on plaquenil. After taking it, does it make you feel all of sudden really tired? I recently started taking it in September and it seems like after about 5-10 minutes of taking it, I feel super tired and sleepy. I have read about the side effects and I do get the stomache discomfort but is the tiredness normal? Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Can plaquenil cause tiredness Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Does Plaquenil make you tired? DailyStrength Hydroxychloroquine cost cvs Is extreme fatigue a side effect of Plaquenil. ellilu58. They didn't cause tiredness but they made me feel really sick. I had to get my GP to change the. Is extreme fatigue a side effect of Plaquenil - NRAS. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Will you have Fatigue with Plaquenil - eHealthMe. Jun 21, 2015 Hydroxychloroquine Plaquenil and generics can itself cause fatigue in some users, it can interrupt sleep patterns especially by causing more vivid dreams which in turn makes one more tired. The drug can also lower blood counts red cell, white cells and others too which in turn can cause fatigue. Find user ratings and reviews for Plaquenil oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction May 05, 2010 None of these meds make me fatigued. I believe its the illness that causes my fatigue and my daughters fatigue. I suspect that holds true for you too. Maybe someone else will tell you differently, but I haven't known anyone else that found Plaquenil to make them tired. Pace and rest when you can and if you can exercise a little try to do that.