These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Fundus autofluorescence in hydroxychloroquine toxicity Plaquenil manufacturer meloxicam Chloroquine has been replaced with hydroxychloroquine as it has less side effects. Eye Exam Before Starting Treatment. If a person is going to be treated long-term with Plaquenil, they need to have a thorough dilated eye exam with best corrected visual acuity, central visual field, color vision, and dilated examination of the retina. Chloroquine-induced retinal toxicity was first described in 1959 and the retinal toxic effects of hydroxychloroquine were later described in 1967 3, 4. Hydroxychloroquine has significantly less retinal toxicity and has largely replaced chloroquine as a treatment of inflammatory disease. color vision testing, or on dilated fundus. Retinal toxicity is a very rare side effect of the hydroxychloroquine therapy, but when it has occurred, vision loss may be permanent and may progress even years after the cessation of medication. Patients would be examined every 3 months, then annually, until they are stabled. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Plaquenil color vision effects What can Hydroxychloroquine Plaquenil do to my eyes?, Hydroxychloroquine Plaquenil Toxicity and. Is hydroxychloroquine good when out of dateHydroxychloroquine syrup Aug 30, 2011 Despite cessation of hydroxychloroquine, one-year follow-up revealed a mild worsening visual acuity to 20/30 OD and 20/25 OS, with new abnormalities on Amsler grid and deficits on color vision testing. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Retinal toxicity associated with chronic exposure to.. Plaquenil Indications, Side Effects, Warnings -. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. If you feel like your central vision is getting blurred, if you lose the ability to see a digital clock, if you lose color vision—if reds look kind of washed out—or if you have trouble seeing at night Those are early signs that you might be developing Plaquenil retinopathy,” says Katz. Plaquenil toxicity is very distinctive,” said Michael F. Marmor, MD, professor of ophthalmology at Stanford University. Dr. Marmor, who chaired the Academy’s screening guidelines committee, said the goal in Plaquenil screening is to catch changes at a very early stage when there’s just a minimal amount of loss of vision.