Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Is hydroxychloroquine an anti viral medication Hydroxychloroquine aps Malaria resources pdf fsp drugs chloroquine Side effects to plaquenil With Plaquenil Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 400 mg of Plaquenil daily puts anyone under 135 pounds at a higher risk for toxicity Therefore, 200mg of Plaquenil daily is going to be a safe dosage for virtually all adults13 Multifocal ERG has the ability to detect early macular dysfunction, so it should be included as part of baseline screening. A maximum daily dose of Plaquenil of 5.0mg/kg real weight is recommended. Communication with the prescribing physician is also key to proper treatment and management of your patient. Dec 15, 2004 Multifocal ERG testing can detect abnormal function in chloroquine retinopathy even when the full-field ERG appears normal and visible macular alterations are subtle. The mfERG of patients with retinopathy can be altered in many ways including generalized depression of the mfERG, loss of the central peak waveform, as well as a pericentral loss. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Erg test plaquenil Advanced Multifocal ERG mfERG Diopsys, How to Succeed in Plaquenil Screenings Chloroquine molecular weightHydroxychloroquine drugs.comHow plaquenil helps lupus ph levels The electroretinogram ERG is a diagnostic test that measures the electrical activity generated by neural and non-neuronal cells in the retina in response to a light stimulus. The electrical response is a result of a retinal potential generated by light-induced changes in the flux of transretinal ions, primarily sodium and potassium. Electroretinogram - EyeWiki. Multifocal ERG in Practice. This is Why You Need Multifocal ERG if You Have Plaquenil Patients. Multifocal Electroretinogram mf-ERG This test allows the detection of localized parafoveal or extramacular depression in early retinopathy 10, 15. This has similar sensitivity to visual fields and can provide objective confirmation of suspected paracentral field loss. Apr 20, 2011 2011 Testing Guidelines Since the initial screening and monitoring recommendations were published in 2002, there have been reports of retinal toxicity associated with the use of Plaquenil. Furthermore, the advent of novice sensitive diagnostic modalities has led to a revision of the recommended guidelines for patients using Plaquenil see. ERG for Diagnosis of Birdshot Chorioretinopathy. Tzekov and Madow 2015 stated that birdshot chorioretinopathy BSCR is a rare form of autoimmune posterior uveitis that can affect the visual function and, if left untreated, can lead to sight-threatening complications and loss of central vision.