Why chloroquine start with loading dose

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  1. poppp XenForo Moderator

    Why chloroquine start with loading dose


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. -Each dose should be taken with a meal or a glass of milk.

    Hydroxychloroquine sulfate side effecys Hydroxychloroquine metabolism cyp Hydroxychloroquine retinitis pigmentosa Plaquenil treatment

    Post-exposure prophylaxis Loading dose 1000mg of chloroquine salt 600mg base taken at 0-hours, 24-hours, and then 500mg of chloroquine salt 300mg base at 48-hours. Ongoing treatment 500mg chloroquine salt 300mg base taken daily for 12 days. At such a dosage, a therapeutic concentration of chloroquine might be reached. With our experience on 2000 dosages of hydroxychloroquine during the past 5 years in patients with long-term treatment 1 year, we know that with a dosage of 600 mg/day we reach a concentration of 1 μg/mL 15. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Call your doctor right away if you have any eyesight changes like blurred or foggy eyesight, trouble focusing or reading, or trouble seeing in dim light.

    -Concomitant therapy with an 8-aminoquinoline drug is necessary for the radical cure of vivax and malariae malaria. Use: Malaria prophylaxis Acute attack: 800 mg (620 mg base) orally followed in 6 to 8 hours by 400 mg (310 mg base), then 400 mg (310 mg base) once a day for 2 consecutive days; alternatively, a single dose of 800 mg (620 mg base) has also been effective Alternate dosing based on body weight: A total dose representing 25 mg/kg is administered in 3 days, as follows: First dose: 10 mg base/kg (not to exceed 620 mg base) orally Second dose: 5 mg base/kg (not to exceed 310 mg base) orally 6 hours after first dose Third dose: 5 mg base/kg orally 18 hours after second dose Fourth dose: 5 mg base/kg orally 24 hours after third dose Comments: -Each dose should be taken with a meal or a glass of milk.

    Why chloroquine start with loading dose

    Chloroquine & Hydroxychloroquine supporting chemo effectiveness and., Chloroquine and hydroxychloroquine as available weapons to fight COVID.

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  7. Drugs which may be started with an initial loading dose include digoxin, teicoplanin, voriconazole, procainamide and fulvestrant. One or series of doses that may be given at the onset of therapy with the aim of achieving the target concentration rapidly.

    • Loading dose - Wikipedia.
    • Chloroquine Indications, Side Effects, Warnings -.
    • Chloroquine Dosage - Malaria Home Page.

    Nov 25, 2019 To treat malaria Chloroquine is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. To treat amebiasis Chloroquine is given in a high starting dose for 2 days followed by a smaller dose for 2 to 3 weeks. You may be given other medications to help prevent further infection. Chloroquine phosphate comes as a tablet to take by mouth. For prevention of malaria in adults, one dose is usually taken once a week on exactly the same day of the week. Your doctor will tell you how many tablets to take for each dose. One dose is taken beginning 2 weeks before traveling to an area. Dosage. Chloroquine can be administered either orally or parenterally for treatment of malaria, but prophylaxis is given in tablet form. An effective blood concentration is reached within 2-3 hours if a loading dose of 600 mg base is used. The therapeutically effective plasma concentration is 15-30 m g base/liter.

     
  8. optimist Well-Known Member

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Hydroxychloroquine Side Effects, Dosage, Uses, and More Plaquenil Side Effects Common, Severe, Long Term - Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus
     
  9. bleki XenForo Moderator

    Chloroquine MedlinePlus Drug Information Chloroquine phosphate may cause an upset stomach. Take chloroquine phosphate with food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use chloroquine phosphate exactly as directed. Do not use more or less of it or use it more often than prescribed by your.

    DailyMed - CHLOROQUINE PHOSPHATE tablet