Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine and laser hair removal Plaquenil nerve damage Hydroxychloroquine coupon Plaquenil is used in the treatment of sarcoidosis but its main use is in the treatment of malaria. One of the side effects of taking the drug is that it affects eye sight, and eye tests, especially field of vision tests need to be done every six months. Plaquenil is a mild DMARD disease-modifying anti-rheumatic drug that is very commonly prescribed as a "starter drug" for a wide range of autoimmune conditions. It has a very good overall safety profile and is well-tolerated by most people. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and eye pain Plaquenil and muscle aches and pains?, Experiences taking Plaquenil for Fatigue and Muscle Pain. Humira vs plaquenilCost of antimalarial drugs chloroquineChloroquine phosphate in display tankPlaquenil and imodium I went to my rheumy appt and after 1hr 45 min later all had agreed it was the plaquenil. The strange thing is it had only affected the r eye. And yes i did have a baseline eye exam in oct before i started and then this one after experiencing the pain and pressure. Eye pain. Plaquenil. - HealthBoards. Hydroxychloroquine Plaquenil. Plaquenil Side Effects Common, Severe, Long Term -. As long as you see your eye care professional regularly, you can feel confident that the plaquenil is safe. If any changes occur in the retina, a dye test is ordered to take pictures of the retina to document any changes noted. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Not with Plaquenil, but AS especially and other rheumatoid illnesses are linked to Uveitis. Terribly painful, absolutely nausea inducing and you get light sensitivity with it that is unreal. If you think it could be uveitis google a little then go to the ER, it can damage your vision.