Chloroquine is chloroform

Discussion in 'Canadian Pharcharmy Online' started by megafast, 16-Mar-2020.

  1. HomerS Moderator

    Chloroquine is chloroform


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria β€” a mosquito-borne disease caused by a parasite β€” and to treat amebiasis, an infection of the intestines caused by a parasite. Chloroform is a colorless, sweet-smelling organic compound with the IUPAC name Trichloromethane and formula CHCl3. Chloroform can daze or knock out people even when it’s consumed in small doses. In Third World countries chloroquine phosphate syrup is frequently prepared with chloroform as a preservative. Because of the toxic side effects of chloroform the suitability of a number of possible alternatives were investigated. If the chloroquine phosphate syrup is prepared as such, the combination of sorbic acid 1.5 g/l and citric acid 2 g/l is preferred. If, however, the chloroquine.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine is chloroform

    Chloroquine MedlinePlus Drug Information, How Does Chloroform Work To Knock You Off? Science ABC

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  4. Chloroquine is an aminoquinoline that is quinoline which is substituted at position 4 by a 5-diethylaminopentan-2-ylamino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.

    • Chloroquine C18H26ClN3 - PubChem.
    • The suitability of some preservatives in chloroquine phosphate syrup..
    • Chloroform - epa.gov.

    Chloroquine CAS NO.54-05-7 has long been used in the treatment or prevention of malaria. After the malaria parasite Plasmodium falciparum started to develop widespread resistance to chloroquine, new potential utilisations of this cheap and widely available drug have been investigated. I've tried the magnesium methoxide method and chloroform method on rhodiums page, magnesium methoxide is fucking awful to work with and the chloroform synthesis is prone to thermal runaway. Well today I ran the chloroform synthesis again on a small scale very carefully and got through the addition with no troubles. Chloroform, or trichloromethane, is an organic compound with formula C H Cl 3. It is a colorless, sweet-smelling, dense liquid that is produced on a large scale as a precursor to PTFE. It is also a precursor to various refrigerants. It is one of the four chloromethanes and a trihalomethane.

     
  5. Feniks_MSK Well-Known Member

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Plaquenil Withdrawal – Life As An Anomaly Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Plaquenil Side Effects - GoodRx
     
  6. This is not a list of all drugs or health problems that interact with hydroxychloroquine. Adverse Cutaneous Reactions to Hydroxychloroquine Are More. Hydroxychloroquine Reviews Everyday Health Hydroxychloroquine Oral Route Precautions - Mayo Clinic
     
  7. Archangel Moderator

    Chloroquine Dosage Guide with Precautions - The dose of chloroquine is often expressed or calculated as the base each 500 mg tablet of chloroquine phosphate is equivalent to 300 mg chloroquine base. -The pediatric dose should never exceed the adult dose.

    Aquarium Fish Chloroquine A "New" Drug for Treating Fish.
     
  8. tranquilizator Well-Known Member

    My Take on New Ocular Screening Guidelines for Plaquenil RheumNow. I am lucky as a rheumatologist in practice for more than 30 years to have only had one malpractice lawsuit. But it was for alleged Plaquenil related eye toxicity, and believe me, attornies will grab any guideline they can as "Standard-of-Care" if it suits their case. All to say, we treat patients, not guidelines, but we all need to aware of these.

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