These hard lumps of tissue range in size from about the size of a pea to as large as a ping pong ball. They may develop under the skin over bony areas such as the elbow, ankle, or finger. For some people, treatment with “DMARDs” (disease-modifying antirheumatic drugs) or steroid shots may shrink nodules. Plaquenil monograph Hydroxychloroquine scarring alopecia Plaquenil hyperpigmentation treatment Hydroxychloroquine HCQ has been used to treat systemic lupus erythematosus SLE in Japan since 2015. We herein report a case of SLE that developed generalized pustular psoriasis GPP following the administration of HCQ. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies, or to become more depressed. If you or your caregiver notice any of these side effects, tell your doctor right away. This medicine may cause hypoglycemia low blood sugar. It’s rare, but in some people, nodules are a sign that they have rheumatoid vasculitis, which is inflammation of the small and medium-sized blood vessels. You may need surgery to remove them if they get infected or become painful. Hydroxychloroquine pustular rash Rash from Methotrexate or Hydroxychloroquine? - NRAS, Hydroxychloroquine Plaquenil Side Effects & Dosage for. Plaquenil and tumsChloroquine cancer Acute generalized exanthematous pustulosis AGEP is a rare cutaneous reaction principally induced by drugs. Antibiotics, mainly β-lactams and macrolides, are the most common causative agents, followed by calcium channel blockers and antimalarials. Successful Treatment of Hydroxychloroquine-Induced.. Hydroxychloroquine Oral Route Precautions - Mayo Clinic. Rheumatoid arthritis rash Causes, symptoms, and images. Hydroxychloroquine was reduced to 200 mg/day, methotrexate. Hydroxychloroquine in Psoriasis Is it Really Harmful. pustular drug rash induced by hydroxychloroquine hydroxy- Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness.