While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "I started the hydroxychloroquine medication a week ago and within the first day or two noticed a big difference in my pain and fatigue with major improvement SLE. Plaquenil retinal toxicity treatment What antihistamines can be taken with plaquenil Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. I started on the Plaquenil a little over a week ago. Not much in the way of side effects. Some minor stomach stuff but that could be normal and not related to the Plaquenil. I started at 200mg and increased to 400mg after a week. Andie213, my fatigue has been frustrating for me as well. Hi ellilu, I too am taking Plaquenil and although it has helped with the more severe joint pains and stiffness I am also always fatigued. I was noticing that I'm tired putting a sweater over my head my arms feel tired, showering, driving, getting in and out of my car is a bit tiring. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Fatigue plaquenil PATIENT FACT SHEET Hydroxychloroquine Plaquenil, Experiences taking Plaquenil for Fatigue and Muscle Pain. Dejar de tomar plaquenilHydroxychloroquine-mediated retinopathy Has anyone's doctor suggested Plaquenil for chronic fatigue syndrome? My rheumy has a couple of times. He says it could help with energy level because it is an immune enhancer. My mother took it for rheumatoid arthritis years ago and thinks it's worth a shot. My only concern is the. Plaquenil for CFS. ProHealth Fibromyalgia, ME/CFS and.. Is extreme fatigue a side effect of Plaquenil - NRAS. Hydroxychloroquine Oral Route Description and Brand Names - Mayo Clinic. In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias joint pain, dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” What is Plaquenil and what are its benefits for Sjögren’s patients? Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. I have been on Plaquenil for years. It has not helped me with fatigue. Things like vitamins and exercise might assist with decreasing the fatigue level. I have been on 2 Dmards and a biologic for the longest time. I also take Tramadol for pain and now Indomethicin has been added to the mix to help with stiffness.