Chloroquine cancer therapy

Discussion in 'Canada Drugs Online' started by bacsan, 16-Mar-2020.

  1. Vorgal Guest

    Chloroquine cancer therapy


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy. Maycotte P1, Aryal S, Cummings CT, Thorburn J, Morgan MJ, Thorburn A. Chloroquine CQ is a 4-aminoquinoline drug used for the treatment of diverse diseases. Earlier today, President Trump among others touted chloroquine as a ready-to-use treatment for the disease. To explore this strategy, we reached out to University of Colorado Cancer Center experts who have been at the forefront studying of chloroquine as a possible component of cancer treatment. Chloroquine and hydroxychloroquine, an anti-malarial drug, is in the news today, prominently mentioned during President Trump’s morning press conference. Research does indeed indicate that chloroquine has ‘apparent efficacy and acceptable safety against covid-19 associated pneumonia’, and has shown to help patients recover more quickly.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Chloroquine cancer therapy

    Cancers Free Full-Text Combination Therapy of Chloroquine., Colorado scientists weigh in on chloroquine as possible.

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  5. Mg chloroquine phosphate 300 mg base orally on the same day each week Comments-If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate 600 mg base may be taken orally in 2 divided doses, 6 hours apart.

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    Chloroquine and Cancer Treatment . are well aware of Chloroquine, which is known as one of the most widely and successfully used first generation anti-malarial drug. It is very famous for its effectiveness rather infamous for its characteristic bitter taste, I still remember during my childhood back in India, elders used to threaten. Chloroquine and hydroxychloroquine are drugs that are used to treat malaria, but a new review suggests that they may have another purpose treating cancer. Nov 15, 2015 Summary. Chloroquine is an anti-malarial drug available at pharmacies for people traveling to area with malaria risks. Note based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested.

     
  6. Ladushka XenForo Moderator

    I count calories, and IF works well for me because it allows me to eat "normally" during social meals, which makes it easier to sustain as an eating habit. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Plaquenil & Weight Gain/Loss - Hair loss and Plaquenil? DailyStrength
     
  7. CableMAN New Member

    This is not a list of all drugs or health problems that interact with hydroxychloroquine. Plaquenil and Sun Exposure - Sjogren's World Headache and Sensitive to light Common Related Medical. Plaquenil Side Effects on Your Eyes and Vision
     
  8. HeLeX User

    Hydroxychloroquine sulfate and Drug abuse and dependence. Summary Drug abuse and dependence is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Morphine, and have Alcoholism.

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