It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. The trade name of chloroquine is Plaquenil drug assistance Plaquenil do i need to stop before oral surgery Plaquenil side effects dry skin I have read about people stopping P & flaring up. Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. There is a similar posting on Healthunlocked, "Why oh why did u stop taking plaquenil." You may want to check it out. Can you stop Plaquenil cold turkey" answer - YES. My rheumy told me to take time out on it for a month once. I really don't know why because he only told me to do it the once and I've been on it for six years now He said to give the system a rest for a moth and siad in his experience the disease seemed to be less active in January - so to do. I have had to stop my plaquenil and aside from the fatigue and joint pain that I knew I would have, I also now have a sunburned look on my face when I go out in the sun and itching skin, almost like a hive type rash on my back. Hydroxychloroquine comes as a tablet to take by mouth. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Stopping plaquenil abruptly Hydroxychloroquine Oral Route Description and Brand Names - Mayo Clinic, Can you quit plaquenil cold turkey, or have to wean Plaquenil tab 200 mg caj c 20Aao 2016 plaquenil I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Noticed nothing different. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Let me tell you what weaning down from Plaquenil is like.. Discontinued Plaquenil.itching skin?. Had to stop taking Plaquenil -. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. One of the problems with Plaquenil is that because it's so slow to act, the improvements are also slow and subtle. So most people don't realize that they've improved until they STOP taking it. I've been on it twice, along with Atabrine another antimalarial. In my case, it never worked so I didn't notice a change.