Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. This medication is used to kill the malaria parasites living inside red blood cells. Chloroquine and tonic water Plaquenil and aplastic anemia How long does it take for chloroquine to work What class of drugs is chloroquine Hydroxychloroquine is a medication used to prevent and treat malaria and to treat autoimmune conditions such as rheumatoid arthritis or lupus. Hydroxychloroquine is sold under several brand names, including Plaquenil®. For more information on rheumatoid arthritis or lupus in pregnancy please see. It should be noted that radioactively-tagged chloroquine administered intravenously to pregnant, pigmented CBA mice passed rapidly across the placenta. It accumulated selectively in the melanin. Early reports of in utero chloroquine toxicity have led to some trepidation about the use of HCQ during pregnancy 10, 11. However, more recent systematic studies of HCQ use during pregnancy have suggested its safety 12 - 16. Both drugs may be needed for a complete cure and to prevent the return of infection (relapse). In some cases, you may need to take a different medication (such as primaquine) to kill the malaria parasites living in other body tissues. Chloroquine in pregnancy Is chloroquine safe in pregnancy -, PLAQUENIL® Alternative to plaquenil for raSle on plaquenilPlaquenil msdsAutophagy inhibitors chloroquineBest alternative to plaquenil Geriatric. Although appropriate studies on the relationship of age to the effects of chloroquine have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of chloroquine in the elderly. However, elderly patients are more likely to have age-related kidney problems. Chloroquine Oral Route Before Using - Mayo Clinic. Hydroxychloroquine in lupus pregnancy - Clowse - 2006.. Azithromycin-chloroquine and the intermittent preventive.. Pregnancy. There are no adequate and well-controlled studies evaluating the safety and efficacy of chloroquine in pregnant women; usage during pregnancy should be avoided except in prophylaxis or treatment of malaria when benefit outweighs potential risk to fetus. Lactation Chloroquine phosphate is a 4-aminoquinolone that acts by inhibiting heme polymerase. 198 Chloroquine is well tolerated and in appropriate doses may be safely used by young children and pregnant women. 199 Transient nausea or vomiting is seen in a small proportion of individuals and may usually be reduced by taking the drug with food. Occasionally, headaches or blurred vision are reported. Chloroquine, although grouped with hydroxychloroquine in table 2 of this article, is not routinely used in the management of SLE either in or out of pregnancy due to increased tissue deposition and increased risk of retinal toxicity and of fetal abnormalities 10 - 11.